p-Toluenesulfonyl isocyanate 98.5% (PTSI, CAS 4083-64-1) is a colourless transparent reactive liquid with isocyanate group. It is a high-activity organic intermediate, widely used in pharmaceutical synthesis, pesticide, polyurethane and fine chemical manufacturing. It reacts violently with water, needs strict moisture-proof operation. TNJ Chemical is the leading manufacturer and exporter since from 2001. We guarantee high quality, competitive price, stable supply, fast delivery and tech support etc. To find more, please contact sales@tnjchem.com
Product Information
Chemical Name: p-Toluenesulfonyl isocyanate
Synonyms: PTSI, Tosyl isocyanate, 4-Methylbenzenesulfonyl isocyanateCAS No.: 4083-64-1
EINECS: 223-810-8
Molecular Formula: C₈H₇NO₃S
Molecular Weight: 197.21
Grade: Industrial grade, synthesis gradePurity: ≥98.5%
Chemphysical Properties
Appearance: Colourless transparent liquid
Density (20℃): 1.295 g/cm³
Melting Point: 5 °C
Boiling Point: 288 °C
Flash Point: 145 °C
Refractive Index: 1.533–1.535
Solubility: Reacts with water; miscible with most organic solvents
Feature: Highly reactive, sensitive to moisture, corrosive, releases CO₂ when contacting water
Quality Specification
| Item | Specification |
|---|---|
| Assay | ≥98.5% |
| Color (APHA) | ≤20 |
| p-Toluenesulfonyl chloride | ≤1.0% |
| Moisture | ≤0.1% |
Use & Application
Pharmaceutical intermediate for urea, sulfonamide and API synthesis
Pesticide intermediate for herbicide & fungicide raw materials
Modifier for polyurethane, used to prepare special adhesive and coating
Analytical reagent for hydroxyl / amine group detection
Dehydrating agent in organic synthesis
Packing
20kg HDPE drum, 200kg steel drum with PTFE lining; small aluminium bottle for lab trial.
Delivery & Storage
Storage: Hermetically sealed, cool and dry nitrogen-sealed warehouse.
Strictly keep away from water, moisture, alcohol, amine, strong alkali.
Transport: Hazardous chemical (corrosive, moisture-sensitive).
Avoid rain and leakage, separate from water-containing goods.
Shelf life: 12 months under proper sealed storage.




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