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N,N-Dicyclohexylcarbodiimide CAS 538-75-0
  • CAS:

    538-75-0
  • Summenformel:

    C13H22N2
  • Qualitäts-Standard:

    Enterprise Standard
  • Verpackung:

    25 kg/drum
  • Schneemobil-Bestellung:

    25kgs
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    sales@tnjchem.com
  • Manufacturer:

    TNJ Chemical

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  • Produkt-Details

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N,N-Dicyclohexylcarbodiimide is white crystal or slightly yellow transparent liquid. Melting point 35-36°C, boiling point 154-156°C (1.47kPa), 98-100°C (66.7kPa). It is soluble in benzene, ethanol, ether, but insoluble in water.


Specification

Melting point                         34-35°C(lit.)
Boiling point                          122-124°C6mmHg(lit.)
Density                                 1.247g/mLat25°C
Refractive index                     n20/D1.48
Flash point                            190°F
Storage conditions                 StoreatRT.
Form                                    Waxy Solid or Crystalline Mass
Color                                    Whitet or pale yellow
Water solubility                     Reaction
Sensitivity                            Moisture Sensitive

Application

Mainly used for the condensation of amino acids in the artificial synthesis of peptides. For example, in Fmoc-solid phase synthesis, the carboxyl group of an amino acid forms an amide bond with the amino group of another amino acid. In order to make the carboxyl group more susceptible to attack by nucleophiles, the negatively charged oxygen atom needs to be activated by Chemicalbook to become a better leaving group. DCC plays this role. The oxygen atom of the carboxyl group on the amino acid acts as a nucleophile to attack the carbon atom in the middle of the DCC molecule to combine DCC with the carboxyl group to form an ester structure, making the nucleophilic attack of the amino group easier


Packaging

25 kg/drum

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      N,N-Dicyclohexylcarbodiimide CAS 538-75-0
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